Preheat the oven to 400°F. Line a baking sheet with parchment paper and set aside.
Place broccoli in a bowl and toss with the olive oil. Place on a baking sheet and roast for 15-20 minutes until broccoli is starting to brown. Set aside.
Cook quinoa according to package directions in vegetable or chicken broth.
While quinoa is cooking, add olive oil to a nonstick skillet and heat over medium heat. Salt and pepper the chicken tenders and add to the skillet. Cook, stirring occasionally until just cooked for about 5 minutes.
Lower oven temperature to 350°F.
In a large bowl, combine the quinoa, milk, greek yogurt, half of the cheese, and red pepper flakes. Add the broccoli and chicken. Taste and adjust seasonings.
Pour the mixture into a baking dish and top with remaining cheese. Sprinkle with breadcrumbs.
Bake uncovered until the cheese is melted and heated through about 15-20 minutes.